I'm not an expert but I think that the CPU reserved three adresses :
$FFFA : NMI vector - address to go when NMI (Non Maskable Interrupt) occurs
$FFFC : RESET vector - address to go when starting or resetting the NES
$FFFE : IRQ/BRK vector - don't know when it is useful
Anyway, you shall look at the
Nesdev Wiki to find your answer, and more specifically
here to see the NES architecture.